PHILADELPHIA —Researchers at the Center of Excellence in Environmental Toxicology (CEET), Perelman School of Medicine at the University of Pennsylvania, have been awarded a $10 million grant from the National Institute for Environmental Health Sciences (NIEHS) over the next four years to study asbestos exposure pathways that lead to mesothelioma, the bioremediation of this hazardous material, and mechanisms that lead to asbestos-related diseases. One of these, mesothelioma, a rare cancer diagnosed in about 3,000 patients each year, is caused almost exclusively by exposure to asbestos. The disease is usually fatal with very poor prognosis once diagnosed.