Director: Anil Vachani, MD, MSCE
The dual mission of the Integrative Health Sciences Facility Core (IHSFC) is to: (i) provide infrastructural support for the translation of basic science observations into human studies and trials with the ultimate aim of detecting, preventing and/or managing diseases induced or exacerbated by environmental exposures, and (ii) “back translate” environmental health questions derived from the community into testable hypotheses for human studies (Figure 1).
Current and prospective investigators interested in extending their research into human studies may access the IHSFC via this web site. Community-based questions relating to healthy individuals or patients will be channeled through the Community Engagement Core (CEC) and framed as scientifically relevant queries to be addressed by CEET investigators using the resources of the IHSFC.
A focus is on predicting who is at risk of exposure, who is at risk for disease, and who will respond to treatment with an emphasis on PREcision Environmental/health Medicine (PREEM).
Using integrated and leveraged resources for human research, the IHSFC provides assistance with a broad range of transdisciplinary services including study design, enrollment of research subjects, human and population exposures, data management, access to biological samples, biostatistical analyses, interpretation of results, and manuscript preparation. IHSFC personnel have particular expertise in case-control studies, specimen processing and quality assurance, and analytic methods for characterizing the relationships among molecular data and clinical outcomes using integrative data management systems.
The IHSFC organizes its services across five interactive groups:
Population Exposure Services (Group 2)
CEET Virtual Biorepository (Group 3)
Biostatistics Group (Group 4)