Kelchtermans J, Aoyama BC, Rice JL, Martin A, Collaco JM, McGrath-Morrow SA. Ambient Air Pollution and Outpatient Morbidities in Bronchopulmonary Dysplasia. Ann Am Thorac Soc. 2024 Jan;21(1):88-93. doi: 10.1513/AnnalsATS.202302-096OC. PMID: 37703519; PMCID: PMC10867919.
View in PubMedPublications
The CEET conducts research that links environmental exposures to adverse outcomes and disease, particularly at susceptible stages across the lifespan, and translates its findings to improve public health. We disseminate our research findings to all stakeholders including community organizations, local, state and federal officials and agencies to affect change in environmental health and public health policies.
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Air Pollution
Asbestos
Choi JK, Vigliaturo R, Gieré R, Pérez-Rodríguez I. Microbe-Mineral Interactions between Asbestos and Thermophilic Chemolithoautotrophic Anaerobes. Appl Environ Microbiol. 2023 Jun 28;89(6):e0204822. doi: 10.1128/aem.02048-22. Epub 2023 Apr 17. PMID: 37184266; PMCID: PMC10304897.
View in PubMedAsthma
Gleeson PK, Morales KH, Buckey TM, Fadugba OO, Apter AJ, Christie JD, Himes BE. Factors associated with aeroallergen testing among adults with asthma in a large health system. J Allergy Clin Immunol Glob. 2023 Sep 9;2(4):100167. doi: 10.1016/j.jacig.2023.100167. PMID: 37841071; PMCID: PMC10570953.
View in PubMedGleeson PK, Morales KH, Hvisdas C, LaCava AF, Harhay MO, Rank MA, Apter AJ, Himes BE. Factors Associated With Asthma Biologic Prescribing and Primary Adherence Among Adults in a Large Health System. J Allergy Clin Immunol Pract. 2023 Jun;11(6):1834-1842.e4. doi: 10.1016/j.jaip.2023.03.003. Epub 2023 Mar 10. Erratum in: J Allergy Clin Immunol Pract. 2023 Dec;11(12):3822-3823. PMID: 36907354; PMCID: PMC10330036.
View in PubMedSchreibman A, Xie S, Hubbard RA, Himes BE. Linking Ambient NO2 Pollution Measures with Electronic Health Record Data to Study Asthma Exacerbations. AMIA Jt Summits Transl Sci Proc. 2023 Jun 16;2023:467-476. PMID: 37350870; PMCID: PMC10283087.
View in PubMedBiomarkers
Pirnie R, P Gillespie K, Mesaros C, Blair IA. Reappraisal of oxidized HMGB1 as a mediator and biomarker. Future Sci OA. 2023 Feb 10;8(10):FSO828. doi: 10.2144/fsoa-2022-0052. PMID: 36874369; PMCID: PMC9979160.
View in PubMedDetlefsen AJ, Paulukinas RD, Penning TM. Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases. Int J Mol Sci. 2023 Jan 18;24(3):1873. doi: 10.3390/ijms24031873. PMID: 36768194; PMCID: PMC9915212.
View in PubMedKao SH, Shofer FS, Greenwood JC, Alomaja O, Ranganathan A, Piel S, Mesaros C, Shin SS, Ehinger JK, Kilbaugh TJ, Jang DH. Cell-Free DNA as a Biomarker in a Rodent Model of Chlorpyrifos Poisoning Causing Mitochondrial Dysfunction. J Med Toxicol. 2023 Oct;19(4):352-361. doi: 10.1007/s13181-023-00956-0. Epub 2023 Jul 31. PMID: 37523031; PMCID: PMC10522542.
View in PubMedClimate Change & Health
Crane K, Li L, Subramanian P, Rovit E, Liu J. Climate Change and Mental Health: A Review of Empirical Evidence, Mechanisms and Implications. Atmosphere (Basel). 2022 Dec;13(12):2096. doi: 10.3390/atmos13122096. Epub 2022 Dec 13. PMID: 37727770; PMCID: PMC10508914.
View in PubMedEnvironmental Justice and Health Disparities
Howarth MV, Eiser AR. Environmentally Mediated Health Disparities. Am J Med. 2023 Jun;136(6):518-522. doi: 10.1016/j.amjmed.2023.02.008. Epub 2023 Feb 23. PMID: 36828212; PMCID: PMC10213113.
View in PubMedEnvironmental Neuroscience
Gladieux M, Gimness N, Rodriguez B, Liu J. Adverse Childhood Experiences (ACEs) and Environmental Exposures on Neurocognitive Outcomes in Children: Empirical Evidence, Potential Mechanisms, and Implications. Toxics. 2023 Mar 10;11(3):259. doi: 10.3390/toxics11030259. PMID: 36977024; PMCID: PMC10055754.
View in PubMedLead
Halabicky OM, Ji X, Gur RE, Gur RC, Yan C, Chen A, Liu J. Childhood lead exposure and sex-based neurobehavioral functioning in adolescence. Neurotoxicology. 2022 Dec;93:1-8. doi: 10.1016/j.neuro.2022.08.008. Epub 2022 Aug 19. PMID: 35988749; PMCID: PMC10433489.
View in PubMedLiu J, Portnoy J, Raine A, Gladieux M, McGarry P, Chen A. Blood lead levels mediate the relationship between social adversity and child externalizing behavior. Environ Res. 2022 Mar;204(Pt D):112396. doi: 10.1016/j.envres.2021.112396. Epub 2021 Nov 18. PMID: 34801542; PMCID: PMC10117419.
View in PubMedLung Cancer
Zhu AY, McWilliams TL, McKeon TP, Vachani A, Penning TM, Hwang WT. Association of multi-criteria derived air toxics hazard score with lung cancer incidence in a major metropolitan area. Front Public Health. 2023 Jun 26;11:1002597. doi: 10.3389/fpubh.2023.1002597. PMID: 37435521; PMCID: PMC10332161.
View in PubMedThompson JC, Vachani A. Could DNA Fragments Be the Key to Early Detection of Lung Cancer? Am J Respir Crit Care Med. 2023 May 1;207(9):1120-1122. doi: 10.1164/rccm.202303-0387ED. PMID: 36883946; PMCID: PMC10161741.
View in PubMedCamiña N, McWilliams TL, McKeon TP, Penning TM, Hwang WT. Identification of spatio-temporal clusters of lung cancer cases in Pennsylvania, USA: 2010-2017. BMC Cancer. 2022 May 17;22(1):555. doi: 10.1186/s12885-022-09652-8. PMID: 35581566; PMCID: PMC9112439.
View in PubMedGillespie KP, Pirnie R, Mesaros C, Blair IA. Cisplatin Dependent Secretion of Immunomodulatory High Mobility Group Box 1 (HMGB1) Protein from Lung Cancer Cells. Biomolecules. 2023 Aug 31;13(9):1335. doi: 10.3390/biom13091335. PMID: 37759736; PMCID: PMC10526420.
View in PubMedPredictive Toxicology
Romano JD, Mei L, Senn J, Moore JH, Mortensen HM. Exploring genetic influences on adverse outcome pathways using heuristic simulation and graph data science. Comput Toxicol. 2023 Feb;25:100261. doi: 10.1016/j.comtox.2023.100261. Epub 2023 Jan 25. PMID: 37829618; PMCID: PMC10569310.
View in PubMedHao Y, Romano JD, Moore JH. Knowledge-guided deep learning models of drug toxicity improve interpretation. Patterns (N Y). 2022 Aug 24;3(9):100565. doi: 10.1016/j.patter.2022.100565. PMID: 36124309; PMCID: PMC9481960.
View in PubMedWindows-of-Susceptibility
Robles-Matos N, Radaelli E, Simmons RA, Bartolomei MS. Preconception and developmental DEHP exposure alter liver metabolism in a sex-dependent manner in adult mouse offspring. Toxicology. 2023 Nov;499:153640. doi: 10.1016/j.tox.2023.153640. Epub 2023 Oct 6. PMID: 37806616; PMCID: PMC10842112.
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