Rose Albert, CEET Trainee and PhD Candidate in Pharmacology, receives F31 award

Shallow Focus Photography of Microscope

Rose Albert, a predoctoral trainee on the CEET T32, is the recipient of an NIH F31 Ruth L. Kirschstein National Research Service Award: F31 HL179994: The role of sex chromosomes in neonatal hyperoxic lung injury. Rose is a PhD Candidate in Pharmacology, working in the lab of Dr. Krithika Lingappan. Her research focuses on environmental exposures and sex differences in lung injury and development.

 F31 HL179994: The role of sex chromosomes in neonatal hyperoxic lung injury

Narrative: Bronchopulmonary dysplasia is a chronic lung disease that primarily affects male preterm neonates and is the most common complication associated with preterm birth. Sex chromosomes can contribute to sex-biased disease outcomes through expression of genes found on chromosomes X and Y. We will determine the role of sex chromosome dosage and the role of an X-linked gene, Kdm6a, in driving sex-specific outcomes in a mouse model of bronchopulmonary dysplasia to provide insight into new mechanisms and therapeutic targets that may be protective against disease.